I recently had a little more time traveling, which has given me the opportunity to catch up on some of my chiropractic research podcasts.
One of the remarkable development of chiropractic research over the last 25 years has been in the basic science department among other places. In particular, while empirically chiropractors and their patients have known for a long time that the manual adjustment is associated with many changes in body chemistry well beyond neuromusculoskeletal markers such as pain reduction and range of motion, trying to document and quantify that has been comparatively lagging behind.
Some of the non-neuromusculoskeletal changes reported by patients often include feeling more energy, sleeping better, feeling less inflamed overall, improved mood and digestion and cognition. While some of those changes are thought to be associated with changes in neurological feedback loops between the brain and the body, this most recent piece of research seems to suggest that there is potentially an additional core biochemical change associated with the chiropractic adjustment, namely the modulation of local free radicals as well as the up regulation of the body's own antioxidant pathways. The research project was unfortunately interrupted by the arrival of the covid pandemic, which did reduce the total sample size of patients, making some of the statistical data a little tough to analyze, however this paper is still a very exciting first step in further investigating how chiropractic care can improve the overall long-term well-being of our patients.
https://pubmed.ncbi.nlm.nih.gov/39966844/
https://pubmed.ncbi.nlm.nih.gov/35760595/